Current progress of source control in the management of intra-abdominal infections.
10.1016/j.cjtee.2020.07.003
- VernacularTitle:Current progress of source control in the management of intra-abdominal infections
- Author:
Xiu-Wen WU
1
,
2
;
Tao ZHENG
1
,
2
;
Zhi-Wu HONG
1
,
2
;
Hua-Jian REN
1
,
2
;
Lei WU
1
,
2
;
Ge-Fei WANG
1
,
2
;
Guo-Sheng GU
1
,
2
;
Jian-An REN
1
,
3
Author Information
1. Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
2. Lab for Trauma and Surgical Infection, Jinling Hospital, Nanjing, China.
3. Lab for Trauma and Surgical Infection, Jinling Hospital, Nanjing, China. Electronic address: JiananR@gmail.com.
- Publication Type:Review
- Keywords:
Intra-abdominal infection;
Open abdomen;
Source control;
Source control failure
- MeSH:
Anti-Bacterial Agents/administration & dosage*;
Drainage;
Fluid Therapy;
Hemodynamics;
Humans;
Intraabdominal Infections/therapy*;
Laparoscopy;
Laparotomy;
Prognosis;
Sepsis
- From:
Chinese Journal of Traumatology
2020;23(6):311-313
- CountryChina
- Language:English
-
Abstract:
Intra-abdominal infection (IAI) is a deadly condition in which the outcome is associated with urgent diagnosis, assessment and management, including fluid resuscitation, antibiotic administration while obtaining further laboratory results, attaining precise measurements of hemodynamic status, and pursuing source control. This last item makes abdominal sepsis a unique treatment challenge. Delayed or inadequate source control is an independent predictor of poor outcomes and recognizing source control failure is often difficult or impossible. Further complicating issue in the debate is surrounding the timing, adequacy, and procedures of source control. This review evaluated and summarized the current approach and challenges in IAI management, which are the future research directions.
