New perspectives on traumatic bone infections.
10.1016/j.cjtee.2020.05.009
- Author:
Ruo-Hui TANG
1
;
Jing YANG
2
;
Jun FEI
3
,
4
Author Information
1. Health Team of 96824 Troops of the Chinese People's Liberation Army, Kunming, China.
2. Emergency Department, Daping Hospital, Third Military Medical University, Chongqing, China.
3. Emergency Department, Daping Hospital, Third Military Medical University, Chongqing, China
4. State Key Laboratory of Trauma, Burns and Combined Injury, Third Military Medical University, Chongqing, China. Electronic address: feijundoctor@sohu.com.
- Publication Type:Review
- Keywords:
Bone destruction;
Bone infection;
Immunomodulation;
Osteoclasts
- MeSH:
Anti-Bacterial Agents/administration & dosage*;
Bone and Bones/metabolism*;
Cellular Microenvironment;
Humans;
Immune System/immunology*;
Lymphocyte Subsets/immunology*;
Osteitis/microbiology*;
Osteoblasts/physiology*;
Osteoclasts/physiology*;
Staphylococcal Infections
- From:
Chinese Journal of Traumatology
2020;23(6):314-318
- CountryChina
- Language:English
-
Abstract:
In this paper, we review the results of previous studies and summarize the effects of various factors on the regulation of bone metabolism in traumatic bone infections. Infection-related bone destruction incorporates pathogens and iatrogenic factors in the process of bone resorption dominated by the skeletal and immune systems. The development of bone immunology has established a bridge of communication between the skeletal system and the immune system. Exploring the effects of pathogens, skeletal systems, immune systems, and antibacterials on bone repair in infectious conditions can help improve the treatment of these diseases.
