A review on cell-based models of human liver disease in vitro.
10.7507/1001-5515.202004027
- Author:
Ting LIU
1
,
2
;
Yuqing GE
2
;
Min YUAN
3
;
Qiao XIONG
4
;
Jianlong ZHAO
2
Author Information
1. School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, P.R.China
2. State Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai 200050, P.R.China.
3. School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, P.R.China.
4. Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai 200433, P.R.China.
- Publication Type:Review
- Keywords:
liver diseases;
liver function;
microenvironment;
model in vitro;
protein biomarkers
- MeSH:
Animals;
Disease Models, Animal;
Humans;
Liver;
Liver Cirrhosis/pathology*;
Liver Neoplasms/pathology*;
Non-alcoholic Fatty Liver Disease/pathology*
- From:
Journal of Biomedical Engineering
2021;38(1):178-184
- CountryChina
- Language:Chinese
-
Abstract:
Unhealthy diet, habits and drug abuse cause a variety of liver diseases, including steatohepatitis, liver fibrosis, liver cirrhosis and liver cancer, which seriously affect human health. The fabrication of highly simulated cell models in vitro is important in the treatment of liver diseases and drug development. This article summarized the common strategies for the construction of liver pathology models
