A Case of Crescentic Glomerulonephritis Superimposed on Membranous Glomerulopathy.
- Author:
A Jin CHO
1
;
Jin Hee LEE
;
Byeongho JEONG
;
Seungmin CHUNG
;
Jung Eun LEE
;
Gee Young KWON
;
Wooseong HUH
;
Yoon Goo KIM
;
Dae Joong KIM
;
Ha Young OH
Author Information
1. Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. ungeun34.lee@samsung.com
- Publication Type:Case Report
- Keywords:
Membranous glomerulopathy;
Nephrotic syndrome;
Immunosuppression
- MeSH:
Acute Kidney Injury;
Adult;
Azotemia;
Biopsy;
Female;
Glomerulonephritis;
Glomerulonephritis, Membranous;
Humans;
Immunosuppression;
Nephrotic Syndrome;
Renal Insufficiency
- From:Korean Journal of Nephrology
2010;29(2):256-259
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Membranous glomerulopathy (MGN) is a common cause of nephrotic syndrome in adults. Renal failure gradually develops in patients with MGN and crescentic glomerulonephritis (CGN) superimposed on MGN is a rare cause of acute renal failure. In most cases patients showed nephrotic syndrome with acute renal failure. We report a 33-year-old woman with azotemia but with no other symptoms such as nephrotic syndrome she had been diagnosed to have MGN 15 months before. There seemed to be no other cause of azotemia. Renal biopsy was performed and revealed CGN on existing MGN. She was treated with immunosuppression treatment and azotemia was improved. When unexplained azotemia develops in patients with MGN, we should promptly investigate superimposed conditions including CGN. In CGN superimposed on MN, a potentially reversible condition with appropriate immunosuppression therapy should be considered.
