Application of biomechanical modeling and simulation in the development of non-invasive technologies and devices for cardiovascular testing.
10.7507/1001-5515.202008076
- Author:
Xujie ZHANG
1
;
Zhonglin GOU
1
;
Tianqi WANG
1
;
Fuyou LIANG
1
Author Information
1. School of Naval Architecture, Ocean & Civil Engineering, Shanghai Jiao Tong University, Shanghai 200240, P.R.China.
- Publication Type:Journal Article
- Keywords:
arterial stiffness;
biomechanical modeling and simulation;
blood pressure;
non-invasive cardiovascular testing
- MeSH:
Arterial Pressure;
Biomechanical Phenomena;
Blood Pressure;
Blood Pressure Determination;
Humans;
Reproducibility of Results;
Risk Factors
- From:
Journal of Biomedical Engineering
2020;37(6):990-999
- CountryChina
- Language:Chinese
-
Abstract:
The prevalence of cardiovascular disease in our country is increasing, and it has been a big problem affecting the social and economic development. It has been demonstrated that early intervention of cardiovascular risk factors can effectively reduce cardiovascular disease-caused mortality. Therefore, extensive implementation of cardiovascular testing and risk factor screening in the general population is the key to the prevention and treatment of cardiovascular disease. However, the categories of devices available for quick cardiovascular testing are limited, and in particular, many existing devices suffer from various technical problems, such as complex operation, unclear working principle, or large inter-individual variability in measurement accuracy, which lead to an overall low popularity and reliability of cardiovascular testing. In this study, we introduce the non-invasive measurement mechanisms and relevant technical progresses for several typical cardiovascular indices (e.g., peripheral/central arterial blood pressure, and arterial stiffness), with emphasis on describing the applications of biomechanical modeling and simulation in mechanism verification, analysis of influential factors, and technical improvement/innovation.
