Design and mechanical properties of biodegradable polymeric stent.
10.7507/1001-5515.202009039
- Author:
Yu CHEN
1
;
Guanshi WANG
1
;
Chong CHEN
1
;
Anqiang SUN
2
;
Wentao FENG
2
;
Wentao JIANG
1
Author Information
1. Department of Mechanical Science and Engineering, Sichuan University, Chengdu 610065, P.R.China.
2. School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, P.R.China.
- Publication Type:Journal Article
- Keywords:
biodegradable;
configuration;
mechanical properties;
polymer;
stent
- MeSH:
Absorbable Implants;
Animals;
Percutaneous Coronary Intervention;
Polymers;
Prosthesis Design;
Stents
- From:
Journal of Biomedical Engineering
2020;37(6):967-973
- CountryChina
- Language:Chinese
-
Abstract:
Biodegradable stents (BDSs) are the milestone in percutaneous coronary intervention(PCI). Biodegradable polymeric stents have received widespread attention due to their good biocompatibility, moderate degradation rate and degradation products without toxicity or side effects. However, due to the defects in mechanical properties of polymer materials, the clinical application of polymeric BDS has been affected. In this paper, the BDS geometric configuration design was analyzed to improve the radial strength, flexibility and reduce the shrinkage rate of biodegradable polymeric stents. And from the aspects of numerical simulation, in vitro experiment and animal experiment, the configuration design and mechanical properties of biodegradable polymeric stents were introduced in detail in order to provide further references for the development of biodegradable polymeric stents.
