Mandibular Enlargement, Metastatic Pulmonary Calcification and Gastric Mucosal Calcinosis in a Patient with Chronic Kidney Disease-mineral Bone Disorder.
- Author:
Jeong Yup KIM
1
;
Jeong Seon KIM
;
Joon Kwang WANG
;
Sang Won PARK
;
Young Mo LEE
;
Ji Eun LEE
;
Eun Sil JEON
;
Heui Jung PYO
;
Young Joo KWON
;
Jae Bok LEE
Author Information
1. Division of Nephrology, Department of Internal Medicine, College of Medicine, Korea University, Korea. yjkwon@korea.ac.kr
- Publication Type:Case Report
- Keywords:
Secondary hyperparathyroidism;
Pathologic calcification
- MeSH:
Calcinosis;
Calcium;
Humans;
Hyperparathyroidism;
Hyperparathyroidism, Secondary;
Kidney;
Kidney Transplantation;
Parathyroidectomy;
Phosphorus;
Renal Insufficiency, Chronic
- From:Korean Journal of Nephrology
2010;29(2):270-275
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Secondary hyperparathyroidism is one of the most common complications of patients with chronic kidney disease (CKD). Mandibular enlargement, metastatic pulmonary calcification, and gastric mucosal calcinosis are rare complications in these patients. The defect of calcium and phosphorus metabolism may precipitate pathologic calcification at diverse organs and soft tissue, and change bone architecture. In case of involving periarticular area, patients usually present with localized swelling, pain, and reduced mobility in affected sites. However, in case of organ involvement, except in an advanced stage of disease, there are no specific symptoms. Among these patients, treatment strategies include tight control of calcium and phosphate levels, parathyroidectomy for hyperparathyroidism, renal transplantation, and local excision of calcific lesions. We report a case of mandibular enlargement, metastatic pulmonary calcification, and gastric mucosal calcinosis due to CKD with improvement 3 months after medical and surgical treatment.
