Expert consensus on Antiviral Oral Liquid in treatment of influenza in clinical practice.
10.19540/j.cnki.cjcmm.20200927.501
- Author:
You-Ran LU
1
;
Qing-Quan LIU
2
;
Guo-Zhen ZHAO
1
;
Yi-Shan CHEN
1
;
Li-Yun HE
3
;
Yu-Guang WANG
1
;
Ze-Huai WEN
4
;
Zeng-Tao SUN
5
;
Qin LI
6
;
Hui-Yong ZHANG
7
Author Information
1. Beijing Hospital of Traditional Chinese Medicine, Capital Medical University Beijing 100010, China.
2. Beijing Hospital of Traditional Chinese Medicine, Capital Medical University Beijing 100010, China Beijing Key Laboratory of Basic Research on Infectious Diseases of Traditional Chinese Medicine Beijing 100010, China Beijing Institute of Traditional Chinese Medicine Beijing 100010, China.
3. Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences Beijing 100700, China.
4. Traditional Chinese Medicine Hospital of Guangdong Province Guangzhou 510120, China.
5. Tianjin University of Traditional Chinese Medicine Tianjin 300193, China.
6. Fuzhou Infectious Disease Hospital Fuzhou 350025, China.
7. Longhua Hospital, Shanghai University of Traditional Chinese Medicine Shanghai 200032, China.
- Publication Type:Systematic Review
- Keywords:
Antiviral Oral Liquid;
GRADE;
clinical practice;
expert consensu;
influenza
- MeSH:
Antiviral Agents/therapeutic use*;
Consensus;
Hand, Foot and Mouth Disease;
Humans;
Influenza, Human/drug therapy*;
Medicine, Chinese Traditional
- From:
China Journal of Chinese Materia Medica
2021;46(9):2304-2308
- CountryChina
- Language:Chinese
-
Abstract:
Antiviral Oral Liquid is modified on the basis of Baihu Decoction in Treatise on Febrility Diseases by ZHANG Zhongjing and Qingwen Baidu Yin in Qing Dynasty, with effects in clearing toxic heat, repelling dampness and cooling blood. It is widely used in clinical treatment of common colds, influenza and upper respiratory tract infection, mumps, viral conjunctivitis and hand-foot-mouth disease, with a good clinical efficacy and safety. Based on a questionnaire survey of clinicians and a systematic review of study literatures on Antiviral Oral Liquid, the international clinical practice guidelines development method was adopted to analyze the optimal available evidences and expert experiences in the "evidence-based, consensus-based and experience-based" principles. The consensus was jointly reached by more than 30 multidisciplinary experts nationwide, including clinical experts of traditional Chinese and Western medicine in the field of respiratory diseases and infectious diseases, and methodological experts. In the study, literatures were retrieved based on clinical problems in the clinical survey as well as PICO clinical problems. The GRADE system was used for the classification and evaluation of evidence, and fully combined with clinical expert experience, so as to reach expert consensus by the nominal grouping method. This expert consensus recommended or suggested indications, usage and dosage, course of treatment, intervention time for treatment, and the safety and precautions of Antiviral Oral Liquid for treatment of influenza, and can provide reference for the rational use of this drug in clinical practice.