Overview of metalomics research and its application prospect in mineral Chinese medicine research.
10.19540/j.cnki.cjcmm.20200106.601
- Author:
Yu-Lu MA
1
;
Fang FANG
1
;
Sheng-Jin LIU
1
;
Zhi-Jie ZHANG
2
;
Rui-Chao LIN
3
;
AO WULIJI
4
;
De-Kang WU
1
;
Jin-Ao DUAN
1
Author Information
1. State Administration of Traditional Chinese Medicine Key Laboratory of Chinese Medicinal Resources Recycling Utilization,National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, School of Pharmacy,Nanjing University of Chinese Medicine Nanjing 210023, China.
2. Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
3. College of Chinese Materia Medica, Beijing University of Chinese Medicine Beijing 102488, China.
4. Inner Mongolia University for Nationalities Tongliao 028000, China.
- Publication Type:Journal Article
- Keywords:
inorganic element;
material base;
mechanism of action;
metal ions;
metallic element;
metallomics;
mineral Chinese medicine(MCM)
- MeSH:
China;
Drugs, Chinese Herbal;
Medicine, Chinese Traditional;
Minerals;
Quality Control
- From:
China Journal of Chinese Materia Medica
2021;46(9):2142-2148
- CountryChina
- Language:Chinese
-
Abstract:
Metallomics is a frontier interdisciplinary subject at its vigorous development stage. Its goal is to systematically study the content, distribution, chemical species, structural characteristics and functions of metal elements in biological system. It is also a comprehensive discipline to study the existing state and function of free or complex metal elements in life. Metallomics is an ideal tool to study the biological behavior of inorganic elements, which can be used to solve many problems in the research of mineral Chinese medicine(MCM). It provides a strong theoretical basis and technical support for the research of MCM. Its theory and methods provide re-ference and enlightenment for the in-depth study of MCM, and also provide new ideas and open up new ways for the research of MCM. The application of metallomics theory and methods in the research of MCM is of great significance to reveal the material basis and mec-hanism of MCM, promote the process of basic research on MCM, fully exploit and utilize medicinal mineral resources and carry forward the traditional MCM treasure in China. In this paper, we introduced the concept, academic development, research content and research methods of metallomics, and discussed the application prospects of metallomics in the analysis of inorganic element composition characteristics and quality control, material basis and mechanism of MCM, so as to provide reference for further researches on MCM.
