Extraction and separation, structure analysis and biological activity of polysaccharides from Atractylodis Rhizoma.
10.19540/j.cnki.cjcmm.20210108.603
- Author:
Li-Kun CHANG
1
;
Wen-Jin ZHANG
2
;
Ye CAO
3
;
Sheng WANG
2
;
Chuan-Zhi KANG
2
;
Li ZHOU
2
;
Quan YANG
4
;
Liang-Yun ZHOU
4
;
Lan-Ping GUO
2
Author Information
1. School of Traditional Chinese Medicine, Guang Dong Pharmaceutical University Guangzhou 510006, China National Resource Center for Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
2. National Resource Center for Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
3. School of Pharmacy, Anhui University of Chinese Medicine Hefei 230012, China.
4. School of Traditional Chinese Medicine, Guang Dong Pharmaceutical University Guangzhou 510006, China.
- Publication Type:Journal Article
- Keywords:
Atractylodis Rhizoma;
extraction;
polysaccharides;
purification and separation;
structural characteristics
- MeSH:
Atractylodes;
Drugs, Chinese Herbal;
Polysaccharides;
Rhizome;
Triterpenes
- From:
China Journal of Chinese Materia Medica
2021;46(9):2133-2141
- CountryChina
- Language:Chinese
-
Abstract:
Atractylodis Rhizoma(AR) is a traditional Chinese medicinal material for food and medicine, with the functions of eli-minating dampness, strengthening the spleen, expelling wind evil and dispersing cold. AR contains a variety of compounds, including sesquiterpenoids, alkynes, triterpenoids, aromatic glycosides, polysaccharides and so on. At present, the researches on AR mainly focus on volatile components, with relatively fewer researches on non-volatile components. Polysaccharide from Atractylodis Rhizoma(ARP) is an important material basis among non-volatile components for the efficacy. Due to its many biological activities such as immunomodulatory activity, anti-tumors, anti-virus and anti-oxidation, ARP has certain research value and potential. The diversity of the polysaccharide structure is the basis for biological functions, but it also increases the difficulty of carbohydrate research. The research on the extraction, separation, purification, structure and activity of ARP is in the preliminary exploration stage, still with many shortcomings. Herein, recent advancements in the extraction, purification, structural characteristics and biological activities of ARP were summarized in this article to provide scientific reference for the in-depth systematic research of ARP and the development of AR resources.
