A new alkaloid from Ervatamia hainanensis.
10.19540/j.cnki.cjcmm.20210125.602
- Author:
Zi-Wei LI
1
;
Chen-Chen SANG
1
;
Biao SUN
1
;
Hai-Yan TIAN
1
;
Xiao-Qi ZHANG
2
;
Wen-Cai YE
2
Author Information
1. Institute of Traditional Chinese Medicine & Natural Products, and Guangdong Engineering Research Center for Modernization of Traditional Chinese Medicine(TCM), College of Pharmacy, Jinan University Guangzhou 510632, China.
2. Institute of Traditional Chinese Medicine & Natural Products, and Guangdong Engineering Research Center for Modernization of Traditional Chinese Medicine(TCM), College of Pharmacy, Jinan University Guangzhou 510632, China NMPA Key Laboratory for Quality Evaluation of TCM (Traditional Chinese Patent Medicine) Guangzhou 510632, China.
- Publication Type:Journal Article
- Keywords:
10-hydroxydemethylhirsuteine;
Ervatamia hainanensis;
chemical constituent;
monoterpenoid indole alkaloid
- MeSH:
Alkaloids;
Chromatography, High Pressure Liquid;
Molecular Structure;
Plant Leaves;
Tabernaemontana
- From:
China Journal of Chinese Materia Medica
2021;46(10):2509-2513
- CountryChina
- Language:Chinese
-
Abstract:
In order to study the alkaloids from branches and leaves of Ervatamia hainanensis, silica gel, ODS, Sephadex LH-20 and HPLC chromatography were used to obtain six alkaloids from the branches and leaves of E. hainanensis with use of. Based on the physicochemical properties and spectral data, their structures were identified as 10-hydroxydemethylhirsuteine(1), 3R-hydroxycoronaridine(2), 3-(2-oxopropyl)coronaridine(3), pandine(4), 16-epi-vobasine(5), and 16-epi-vobasinic acid(6). Among them, compound 1 was a new monoterpenoid indole alkaloid, and compounds 5 and 6 were obtained from this plant for the first time.
