Structural Chinese medicine: new research field on pharmacodynamic substance basis of traditional Chinese medicine.
10.19540/j.cnki.cjcmm.20210129.601
- Author:
Hong-Zhi QIAO
1
;
Liu-Qing DI
2
;
Qi-Neng PING
3
;
Li-Hong HU
4
Author Information
1. Jiangsu Engineering Research Center for Efficient Delivery System of Traditional Chinese Medicine, School of Pharmacy, Nanjing University of Chinese Medicine Nanjing 210023, China Jiangsu Key Laboratory for Functional Substance of Chinese Medicine Nanjing 210023, China.
2. Jiangsu Engineering Research Center for Efficient Delivery System of Traditional Chinese Medicine, School of Pharmacy, Nanjing University of Chinese Medicine Nanjing 210023, China.
3. School of Pharmacy, China Pharmaceutical University Nanjing 211198, China.
4. Jiangsu Key Laboratory for Functional Substance of Chinese Medicine Nanjing 210023, China.
- Publication Type:Journal Article
- Keywords:
carbonized traditional Chinese medicine;
decoction;
exosomes;
nanotechnology;
pharmacodynamic substance;
phase state;
quality control;
structural Chinese medicine;
supramolecules;
traditional Chinese medicine preparation;
unification of medicines and excipients
- MeSH:
Drugs, Chinese Herbal/pharmacology*;
Medicine, Chinese Traditional
- From:
China Journal of Chinese Materia Medica
2021;46(10):2443-2448
- CountryChina
- Language:Chinese
-
Abstract:
The research on the pharmacodynamic substance basis of traditional Chinese medicine(TCM) is a key scientific issue for the inheritance and development of TCM. At present, a large number of remarkable achievements have been made in the field of chemical components in Chinese medicine, however, another important aspect, namely the physical structure and mode of action of the multi-component assembly of TCM, has not been clearly understood and deeply studied. From the bottleneck of restricting material ba-sic research, we objectively analyzed the common cause of the existing problems. Based on the new discoveries and advances of active substances from TCM emerging in recent years, we extracted and summarized the concept of structural Chinese medicine, elaborated the basic ideas, main features and research modes, hoping to provide theoretical and practical references for the study on the pharmacodynamic substance basis and other research fields of TCM.
