Research progress on active components and mechanism of Isatidis Radix for influenza virus.
10.19540/j.cnki.cjcmm.20201230.601
- Author:
Jiu-Ling DENG
1
;
Yu-Long TAO
1
;
Yu-Qiong HE
1
;
Wan-Sheng CHEN
1
Author Information
1. Shanghai University of Traditional Chinese Medicine Shanghai 201200, China.
- Publication Type:Journal Article
- Keywords:
Isatidis Radix;
active component;
influenza virus;
pharmacological effect
- MeSH:
Antiviral Agents/pharmacology*;
Drugs, Chinese Herbal;
Isatis;
Orthomyxoviridae;
Plant Roots;
Polysaccharides
- From:
China Journal of Chinese Materia Medica
2021;46(8):2029-2036
- CountryChina
- Language:Chinese
-
Abstract:
Isatidis Radix is the dried root of the Isatis indigotica, with pharmacological effects such as heat-clearing and detoxification, cooling blood and pharyngeal relief, antibacterial and anti-inflammatory effects. It is often used clinically to prevent and treat influenza and other diseases. In this paper, relevant domestic and foreign literatures in recent years were summarized, and it was found that Isatidis Radix lignans, indole alkaloids, polysaccharides, etc. were the main active components against influenza virus. Then its pharmacological effects and the mechanism of action were reviewed, providing a basis for in-depth research on the antiviral effect of Isatidis Radix.
