A Study on Dose Response of MAGAT (Methacrylic Acid, Gelatin Gel and THPC) Polymer Gel Dosimeter Using X-ray CT Scanner.
- Author:
Jae Yong JUNG
1
;
Choong Il LEE
;
Jeong Hwan MIN
;
Yon Lae KIM
;
Seong Yong LEE
;
Tae Suk SUH
Author Information
1. Department of Biomedical Engineering, School of Medicine, The Catholic University of Korea, Seoul, Korea. suhsanta@catholic.ac.kr
- Publication Type:Original Article
- Keywords:
MAGAT gel dosimeter;
X-ray CT;
N(CT)-dose response;
Scan parameter
- MeSH:
Gelatin;
Noise;
Polymers;
Tomography Scanners, X-Ray Computed;
Water
- From:Korean Journal of Medical Physics
2010;21(1):1-8
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In this study, we evaluated the dose response of MAGAT (Methacrylic Acid Gelatin gel and THPC) normoxic polymer gel dosimeters based on the X-ray CT scanner. To perform this study, we determined the proper ratio of the gel composition and acquired X-ray scan parameters. MAGAT gel dosimeters were manufactured using MAA (MethacrylicAcid) and gelatin of various concentration, irradiated up to 20 Gy. We obtained the 20 CT images from the irradiated gel dosimeters by using on a Phillips Brilliance Big Bore CT scanner with the various scan parameters. This CT images were used to determine the N(CT)-dose response, dose sensitivity and dose resolution As an amount of MAA and gelatin were increase, the slope and intercept were increase in each MAGAT gel dosimeter with various concentration of the N(CT)-dose response curve. The dose sensitivity was 0.38+/-0.08 to 0.859+/-0.1 and increased were amount of the MAA was increased or the gelatin was decreased. However, the change of gelatin concentration was very small compare to MAA. The Dose resolution (D(delta)(95%)) varies considerably from 2.6 to 6 Gy, dependent on dose resolution and CT image noise. The slope and dose sensitivity was almost ident verywith the variation of the tube voltage, tube current and slice thickness in the dose response curve, but the noise (standard deviation of averamalg CT number) was decreased when the tube voltage, tube current and slice thickness are increase. The optimal MAGAT polymer gel dosimeter based on the CT were evaluated to determine the CT imaging scan parameters of the maximum tube voltage, tube current and slice thickness (commonly used in clinical) using the composition ratio of a 9% MAA, 8% gelatin and 83% water. This study could get proper composition ratio and scan parameter evaluating dose response of MAGAT normoxic polymer gel dosimeter using CT scanner.
