Two new sucrose cinnamates from Polygonum lapathifolium var. salicifolium.
10.19540/j.cnki.cjcmm.20200717.201
- Author:
Zhi-Hua CHEN
1
;
Guo-En WANG
2
;
Ren-Wang JIANG
2
Author Information
1. Guangzhou Baiyunshan Guanghua Pharmaceutical Co.,Ltd. Guangzhou 510285,China Institute of Traditional Chinese Medicine and Natural Products,Jinan University Guangzhou 510632,China.
2. Institute of Traditional Chinese Medicine and Natural Products,Jinan University Guangzhou 510632,China.
- Publication Type:Journal Article
- Keywords:
Polygonum lapathifolium var.salicifolium;
antioxidant activity;
chemical constituent;
sucrose cinnamates
- MeSH:
Antioxidants;
Cinnamates;
Esters;
Molecular Structure;
Polygonum;
Sucrose
- From:
China Journal of Chinese Materia Medica
2021;46(4):944-950
- CountryChina
- Language:Chinese
-
Abstract:
Two new sucrose cinnamates(1 and 2) along with nine known compounds(3-11) were isolated from ethanol extract of Polygonum lapathifolium var. salicifolium by silica gel column chromatography, ODS column chromatography and semi-preparative HPLC. Their structures were elucidated by extensive spectroscopic methods including 1 D-and 2 D-NMR experiments, as well as HR-ESI-MS analysis. Eleven compounds(7 sucrose cinnamates, 3 phenylpropanoids and 1 lactone) were obtained and their structures were identified as(1,3-O-di-p-coumaroyl)-β-D-fructofuranosyl-(2→1)-α-D-glucopyranoside(1),(1,3-O-di-p-coumaroyl)-β-D-fructofuranosyl-(2→1)-(6-O-acetyl)-α-D-glucopyranoside(2),(3-O-feruloyl)-β-D-fructofuranosyl-(2→1)-(6-O-p-coumaroyl)-α-D-glucopyranoside(3), hydropiperoside(4), vanicoside C(5),(1,3-O-di-p-coumaroyl)-β-D-fructofuranosyl-(2→1)-(6-O-feruloyl)-α-D-glucopyranoside(6), vanicoside B(7),trans-p-hydroxycinnamic acid methyl ester(8), trans-p-hydroxycinnamic acid ethyl ester(9), methyl ferulate(10) and dimethoxydimethylphthalide(11), respectively. Compounds 1 and 2 were two new sucrose cinnamates, and compounds 1-11 were isolated from this plant for the first time. The antioxidant activities of the isolated compounds 1-9 were investigated by an oxygen radical absorbance capacity(ORAC) assay, and all nine compounds were found to show strong antioxidant activities. Among them, compound 6(10 μmol·L~(-1)) was the supreme one in antioxidant activities, with its ORAC value equivalent to(1.60±0.05) times of 50 μmol·L~(-1) Trolox.
