Study on quality standard of gypenosides extract and Gypenosides Tablets.
10.19540/j.cnki.cjcmm.20200922.302
- Author:
Zi-Long ZHANG
1
;
Wen-Shan LI
2
;
Fei TENG
3
;
Yan-Hui KUANG
2
;
Dong-Dong FAN
3
;
De-Qin WANG
2
;
Jing-Jing ZHU
3
;
Zhi-Min WANG
3
Author Information
1. Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China Shaanxi University of Chinese Medicine Xianyang 712046, China.
2. Hutchison Whampoa Guangzhou Baiyunshan Chinese Medicine Co., Ltd. Guangzhou 510515, China.
3. Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
- Publication Type:Journal Article
- Keywords:
Gypenosides Tablets;
HPLC;
TLC;
content determination;
gypenoside A;
gypenosides extract
- MeSH:
Gynostemma;
Plant Extracts;
Reference Standards;
Tablets
- From:
China Journal of Chinese Materia Medica
2020;45(24):5976-5981
- CountryChina
- Language:Chinese
-
Abstract:
In response to no national standard for Gynostemma pentaphyllum, a market survey was carried out, and 17 batches of gypenosides extract and 29 batches of Gypenosides Tablets on the market were collected. With gypenoside A as an index, the TLC qualitative identification and HPLC quantitative evaluation method of gypenosides extract and tablets was established. Based on the determination results of 17 batches of gypenosides extract and 29 batches of Gypenosides Tablets, the quality standards of gypenosides extract and tablets were formulated respectively, so as to give suggestions for improving the quality standards of gypenosides extract and tablets. Compared with the existing ministerial standards, the qualitative identification and quantitative detection of specific components were added, in order to provide scientific basis and suggestions for the revision of the quality standard of gypenosides extract and tablet preparation.
