Chemistry research on natural product derivatives of dihydro-β-agarofuran sesquiterpenoids.
10.19540/j.cnki.cjcmm.20200924.202
- Author:
Ruo-Nan NING
1
;
Jia-Qi XU
2
;
Yi-Xin XU
1
Author Information
1. College of Pharmacy, Shanghai University of Medicine & Health Sciences Shanghai 201318, China.
2. Department of Pharmacy, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine Shanghai 200032, China.
- Publication Type:Journal Article
- Keywords:
Euonymus bungeanus;
basic hydrolysis;
dihydro-β-agarofuran sesquiterpenoids
- MeSH:
Biological Products;
Euonymus;
Molecular Structure;
Sesquiterpenes
- From:
China Journal of Chinese Materia Medica
2020;45(23):5712-5721
- CountryChina
- Language:Chinese
-
Abstract:
Dihydro-β-agarofuran sesquiterpenoids possess chemical diversity and biodiversity. A dihydro-β-agarofuran sesquiterpenoid with only hydroxyl groups has been prepared by basic hydrolysis of crude extract of Euonymus bungeanus with 0.4% yield. Twelve derivatives were available in esterification, oxidation, decarboxylation, etc. Extensive ~1H-NMR,~(13)C-NMR, MS spectroscopic analyses and single-crystal X-ray diffraction analysis with Cu Kα radiation indicated that eleven derivatives were new compounds. The results will provide reference for chemistry study on natural product derivatives of dihydro-β-agarofuran sesquiterpenoids.