Phenylpropanoid glycosides from Sophorae Tonkinensis Radix et Rhizoma.
10.19540/j.cnki.cjcmm.20200604.201
- Author:
Sheng-Li YANG
1
;
H E HAO-KE
1
;
Meng-Yin TIAN
1
;
Li XIN
1
;
Su-Juan WANG
1
Author Information
1. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100050, China.
- Publication Type:Journal Article
- Keywords:
Sophorae Tonkinensis Radix et Rhizoma;
constituents;
phenylpropanoids
- MeSH:
Drugs, Chinese Herbal;
Ethanol;
Glycosides;
Rhizome;
Sophora
- From:
China Journal of Chinese Materia Medica
2020;45(22):5525-5529
- CountryChina
- Language:Chinese
-
Abstract:
Three phenylpropanoid glycosides were purified by extensive chromatographic techniques including column chromatography over microporous resin, MCI, diol, sephadex LH-20, reverse phase C_(18) from water-extracts of Sophorae Tonkinensis Radix et Rhizoma. Their planar structures were elucidated by combination of various spectroscopic method, such as IR, UV, MS, and NMR. The absolute configuration of aglycone was determined by quantum chemical calculations. Their structures were elucidated as(8R)-3-(4-hydroxyphenyl)-1-propanol-2-O-β-D-glucopyranoside(1), kalopanaxin D(2),(E)-4-hydroxycinnamyl alcohol 4-O-[2'-O-β-D-apiofuranosyl(1″→2')]-β-D-glucopyranoside(3). Compound 1 was undescribed previously. Compounds 2 and 3 were firstly isolated from Sophora genus.
