Supergenes:Generalists in Gene Expression.
10.3881/j.issn.1000-503X.12419
- Author:
Tao LIU
1
;
Shu Sen WANG
1
;
Lei YANG
2
;
Qiao SHI
3
;
Zhong Yang SHEN
1
Author Information
1. Key Laboratory of Transplant Medicine,Chinese Academy of Medical Sciences,Tianjin First Central Hospital,Tianjin 300192,China.
2. Department of Clinical Laboratory,Tianjin First Central Hospital,Tianjin 300192,China.
3. Graduate School,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China.
- Publication Type:Review
- Keywords:
gene regulation;
non-coding RNA;
supergene;
transcription
- MeSH:
Gene Expression;
RNA, Messenger
- From:
Acta Academiae Medicinae Sinicae
2021;43(2):265-270
- CountryChina
- Language:Chinese
-
Abstract:
In eukaryote cells,transcription from genome DNA is a key process of gene expression.The transcription products contain not only messenger RNAs that code proteins,but also various types of non-coding RNAs.During transcription,some of the gene loci produce more than one kind of RNA molecule,including coding RNAs and more often non-coding RNAs.These gene loci that generate several kinds of RNA molecules are named supergenes.According to the transcription pattern,supergenes are divided into three types,known as types Ⅰ,Ⅱ and Ⅲ.In this review,we summarize the transcription pattern of each type of supergene,and exposit the role of these genes in cells.
