Risk Factors for Patients Using Intraoperative Vasopressor Infusions During Carotid Body Tumor Excision.
10.3881/j.issn.1000-503X.12976
- Author:
Si CHEN
1
;
Jing Jing XU
2
;
Guang Chao GU
3
;
Yue Lun ZHANG
4
;
Jiang SHAO
3
;
Rong ZENG
3
;
Xiao Jun SONG
3
;
Yu Guang HUANG
1
;
Yue Hong ZHENG
3
Author Information
1. Department of Anesthesiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
2. Department of Biomedical Engineering,School of Medicine,Tsinghua University,Beijing 100084,China.
3. Department of Vascular Surgery,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
4. Medical Research Center,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
- Publication Type:Journal Article
- Keywords:
blood pressure;
carotid body tumor;
heart rate;
risk factors;
vasopressor
- MeSH:
Carotid Body Tumor;
Humans;
Retrospective Studies;
Risk Factors;
Treatment Outcome;
Vascular Surgical Procedures
- From:
Acta Academiae Medicinae Sinicae
2021;43(2):199-204
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk factors for patients using intraoperative vasopressor infusions during carotid body tumor(CBT)excision.Patients' mean arterial pressure(MAP)and heart rate(HR)fluctuations as well as their requirements for vasoactive agents during surgery were assessed. Methods The patients receiving CBT excision in Peking Union Medical College Hospital from May 1,2013 to July 31,2017 were included for a retrospective cohort study.The potential factors of intraoperative requirement for vasopressor infusions were investigated using univariate analysis and Logistic multivariate analysis.Furthermore,the relationships of Shamblin types of CBT with intraoperative MAP/HR fluctuations and requirements for vasoactive agents were analyzed. Results A total of 108 patients with 116 CBTs were included.Univariate analysis revealed that maximum tumor diameter >4 cm,intraoperative internal carotid artery injury,internal carotid artery reconstruction,malignant pathology,advanced Shamblin types(type Ⅱ and Ⅲ),estimated blood loss ≥400 ml,and operation duration >4 hours were associated with intraoperative requirements for vasopressor infusions.Logistic analysis showed that Shamblin type Ⅲ(OR=2.286,95% CI=1.324-14.926,P=0.016)and operation duration >4 hours(OR=3.874,95% CI=1.020-14.623,P=0.046)were risk factors for intraoperative requirements for vasopressor infusions during CBT surgery.In addition,Shamblin type Ⅲ was associated with intraoperative abnormal HR elevation and requirements for vasopressors.Conclusions Shamblin type Ⅲ and operation duration>4 hours are risk factors for intraoperative requirements of patients for using vasopressor infusions during CBT surgery.Shamblin type Ⅲ is associated with intraoperative abnormal HR elevation and requirements for vasopressors.
