Advances in Noninvasive Methods for Screening and Evaluating Diabetic Peripheral Neuropathy.
10.3881/j.issn.1000-503X.11477
- Author:
Qian ZHANG
1
;
Xiao Chun LIANG
1
Author Information
1. Department of Traditional Chinese Medicine,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
- Publication Type:Review
- Keywords:
diabetic peripheral neuropathy;
diagnosis;
screening
- MeSH:
Cornea;
Diabetes Mellitus;
Diabetic Foot;
Diabetic Neuropathies/diagnosis*;
Humans;
Mass Screening;
Microscopy, Confocal
- From:
Acta Academiae Medicinae Sinicae
2021;43(1):124-129
- CountryChina
- Language:Chinese
-
Abstract:
Diabetic peripheral neuropathy(DPN),a chronic diabetic microvascular complication with a high incidence among diabetic patients,increases the risk of diabetic foot and amputation.Many methods are available for screening and evaluating DPN,including traditional 10 g monofilament,tuning fork and vibration perception,and tendon reflex tests,which should be combined with some nerve function score systems to improve the detection rate and accuracy for DPN.In recent years,a number of noninvasive new techniques have been developed for the evaluation of nerve injury,such as corneal confocal microscopy,quantitative sensory testing,current perception threshold test,sympathetic sudomotor function evaluation,and quantitative detection of skin advanced glycation end products.This paper reviews these noninvasive methods for screening and evaluating DPN to help clinicians detect and focus on DPN early.
