The Morphologic Changes of Epikeratoplasty Lenticule In a Case.
- Author:
Byung Ro LEE
1
;
Myung Kyu KO
;
Joon Kiu CHOE
Author Information
1. Department of Ophthalmology, School of Medicine Hanyang University, Korea.
- Publication Type:Original Article
- Keywords:
Epikeratoplasty;
Extracellular matrix;
Keratocyte;
Lenticule
- MeSH:
Basement Membrane;
Bowman Membrane;
Cornea;
Corneal Stroma;
Epikeratophakia*;
Extracellular Matrix;
Fluorescent Antibody Technique;
Humans;
Keratoconus;
Microscopy, Electron;
Regeneration;
Trephining;
Wound Healing
- From:Journal of the Korean Ophthalmological Society
1993;34(2):79-84
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The patients initially underwent epikeratoplasty for keratoconus but a penetrating kerato plasty was required due to the opacity in the cornea. By using of this specimen, which was obtained by trephination the healing process of the host-Ienticule cornea could be examined by electron microscopy and immunofluorescence method. Epithelial ingrowth over the lenticule was well formed by the regeneration of the basement membrane over the Bowman's membrane. However, the poor attachment of the lenticule over the host corneal stroma made the interface easily separated during the sectioning processes. Electron microscopic study revealed the keratocytes in the lenticule stroma vacuolized with large number of degenerated microorganelles. These results suggest that it may take a long time to complete the wound healing of the host-Ienticule interface despite the epithelial ingrowth onto the lenticule was well formed.
