Advances in Post-translational Modifications and Endometriosis.
10.3881/j.issn.1000-503X.11427
- Author:
Jing Wen ZHU
1
;
Qing XUE
1
Author Information
1. Department of Gynecology and Obstetrics,Peking University First Hospital,Beijing 100034,China.
- Publication Type:Review
- Keywords:
endometriosis;
pathogenesis;
post-translational modifications
- MeSH:
Acetylation;
Endometriosis/pathology*;
Female;
Glycosylation;
Humans;
Phosphorylation;
Protein Processing, Post-Translational;
Ubiquitination
- From:
Acta Academiae Medicinae Sinicae
2020;42(6):810-814
- CountryChina
- Language:Chinese
-
Abstract:
Proteins exert their roles in life activities via post-translational modifications(PTMs),which include phosphorylation,acetylation,ubiquitination,glycosylation,and methylation.These modifications can change the functions of proteins and play key roles in a variety of diseases.Endometriosis is a common disease in women of childbearing age,although its molecular mechanisms remain unclear.Recent studies have shown that PTMs may be involved in the pathogenesis of endometriosis.Here we review the roles of PTMs in the occurrence and development of endometriosis and the potential medical treatments.
