Clinical Features and Risk Factors of Systemic Lupus Erythematosus Complicated with Cytomegalovirus Infection.
10.3881/j.issn.1000-503X.12267
- Author:
Yu Ting TAN
1
;
Xiao Chun SHI
1
;
Xiao Qing LIU
1
;
Xiao Feng ZENG
2
;
Bao Tong ZHOU
1
Author Information
1. Department of Infectious Diseases, ,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
2. Department of Immunology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
- Publication Type:Journal Article
- Keywords:
cytomegalovirus infection;
risk factors;
systemic lupus erythematosus
- MeSH:
Cyclophosphamide/therapeutic use*;
Cytomegalovirus Infections/epidemiology*;
Humans;
Immunosuppressive Agents/therapeutic use*;
Lupus Erythematosus, Systemic/drug therapy*;
Methylprednisolone/therapeutic use*;
Prednisolone/therapeutic use*;
Retrospective Studies;
Risk Factors;
Serum Albumin, Human/analysis*
- From:
Acta Academiae Medicinae Sinicae
2020;42(6):749-754
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical characteristics and risk factors of systemic lupus erythematosus(SLE)complicated with cytomegalovirus infection(CMV). Methods The medical records of patients diagnosed with SLE at discharge in the Department of Immunology at Peking Union Medical College Hospital between July 1,2017 and April 1,2019 were retrospectively reviewed,and the clinical and laboratory data related to CMV infection were analyzed. Results Of the 231 patients with SLE,115(49.8%)had CMV infection.Among them,78(67.8%)were asymptomatic CMV infection and 37(32.2%)were diagnosed with CMV disease.Univariate analysis showed the number of organs involved(
