Correlation between Vitamin D Status and Gut Microbiota in Patients with Inflammatory Bowel Disease.

Author: Dan CHEN ¹ ; Yue LI ¹ ; Han SUN ² ; Meng XIAO ³ ; Rui Li ZHANG ³ ; Ling QIU ³ ; Bei TAN ¹ ; Jia Ming QIAN ¹
Author Information

1. Department of Gastroenterology, PUMC Hospital, CAMS and PUMC,Beijing 100730,China.
2. Department of Emergency, PUMC Hospital, CAMS and PUMC,Beijing 100730,China.
3. Department of Laboratory,PUMC Hospital, CAMS and PUMC,Beijing 100730,China.
Publication Type:Journal Article
Keywords: gut microbiota; inflammatory bowel disease; vitamin D
MeSH: Bacteria/classification*; Feces/microbiology*; Gastrointestinal Microbiome; Humans; Inflammatory Bowel Diseases/microbiology*; RNA, Ribosomal, 16S/genetics*; Vitamin D/blood*
From: Acta Academiae Medicinae Sinicae 2020;42(6):740-748
CountryChina
Language:Chinese
Abstract: Objective To investigate the correlation between serum total 25-hydroxyvitamin D[T-25(OH)D]level and fecal microbiota in patients with inflammatory bowel disease(IBD). Methods Twenty-three patients with IBD completed the tests for serum T-25(OH)D,and the fecal microbiota was studied using V4 hypervariable region of 16S ribosomal RNA(rRNA)gene sequencing.According to serum T-25(OH)D level,the patients were divided into three groups including vitamin D normal group(