Overview of antibiotic resistance genes database.
- Author:
Bing YANG
1
;
Jing LIANG
2
;
Linmeng LIU
1
;
Xuepei LI
1
;
Quan WANG
3
;
Yi REN
1
Author Information
- Publication Type:Review
- Keywords: antibiotic resistance genes; antibiotics; mobile genetic elements; super bacteria
- MeSH: Anti-Bacterial Agents/pharmacology*; Bacterial Infections; Drug Resistance, Bacterial/genetics*; Drug Resistance, Microbial/genetics*; Humans; Metals
- From: Chinese Journal of Biotechnology 2020;36(12):2582-2597
- CountryChina
- Language:Chinese
- Abstract: The discovery of antibiotics is a big revolution in human history, and its clinical application has saved countless lives. However, with the widespread and abuse of antibiotics, many pathogens have developed resistance, and even "Super Bacteria" resistance to multiple drugs have evolved. In the arms race between humans and pathogens, humans are about to face a situation where no medicine is available. Research on microbial antibiotic resistance genes, resistance mechanisms, and the spread of resistance has attracted the attention of many scientific researchers, and various antibiotic resistance gene databases and analysis tools have emerged. In this review, we collect the current databases that focus on antibiotics resistance genes, and discuss these databases in terms of database types, data characteristics, antibiotics resistance gene prediction models and the types of analyzable sequences. In addition, a few gene databases of anti-metal ions and anti-biocides are also involved. It is believed that this summary will provide a reference for how to select and use antibiotic resistance gene databases.
