Differential discovery strategies of therapeutic antibody drugs.
- Author:
Dong LI
1
Author Information
- Publication Type:Journal Article
- Keywords: differentiation; discovery strategy; drug target; mechanism of action; therapeutic antibody
- MeSH: Drug Delivery Systems; Pharmaceutical Preparations
- From: Chinese Journal of Biotechnology 2020;36(11):2327-2333
- CountryChina
- Language:Chinese
- Abstract: Therapeutic antibody drugs have achieved great success in clinical practice. However, their efficacy and safety still need to be improved. At the same time, excessive concentration of drug targets will cause problems such as repeated development and waste of resources. Therefore, pharmaceutical companies need to explore differentiated discovery strategies when researching antibody drugs in order to survive and develop in the fierce market competition. In this paper, the differential development strategy of therapeutic antibody drugs is discussed from the aspects of drug sources and formats, drug target selection, drug mechanism and differential drug characteristics.
