Advances on mechanism and treatment of salivary gland in radiation injury.

Author: Shen-Sui LI ¹ ; Chen-Zhou WU ¹ ; Xiang-He QIAO ¹ ; Chun-Jie LI ¹ ; Long-Jiang LI ¹
Author Information

1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Head and Neck Oncology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Publication Type:Journal Article
Keywords: apoptosis; aquaporion; radiation injury; radioactive salivatitis
MeSH: Carcinoma, Squamous Cell; Dental Caries; Head and Neck Neoplasms/radiotherapy*; Humans; Mouth Neoplasms; Radiation Injuries; Salivary Glands; Xerostomia/etiology*
From: West China Journal of Stomatology 2021;39(1):99-104
CountryChina
Language:English
Abstract: Oral squamous cell carcinoma (OSCC) is the most frequent tumour in head and neck malignant. The current treatment is mainly based on surgery therapy, radiation therapy and chemical therapy. Meanwhile, there are many a defect in the treatment. For example, there are many defects in radiotherapy. Radioactive salivatitis is the most common. In addition, there are a series of changes such as dry mouth, oral mucositis, rampant dental caries, and radioactive osteomyelitis of jaw, which cause swallowing, chewing problems, and taste dysfunction. Currently, the research on radioactive salivatitis is progressing rapidly, but its mechanism is more complication. This paper review aims to summarize the research progress in this field.