MicroRNA-146a regulates the production of cytokines in lymphocytes stimulated by

Author: Yu-Ting SI ¹ ; Jin-Hua SONG ¹ ; Zhen FANG ² ; Xiao-Zhe HAN ³ ; Shao-Yun JIANG ¹
Author Information

1. Dept. of Periodontology, Hospital of Stomatology, Tianjin Medical University, Tianjin 300070, China.
2. Dept. of Periodontology, Stomatological Center, Peking University Shenzhen Hospital, Shenzhen 518036, China.
3. The Forsyth Institute, Harvard School of Dental Medicine, Cambridge 02146, USA.
Publication Type:Journal Article
Keywords: cytokine; lipopolysaccharide; lymphocytes; microRNA-146a; periodontitis
MeSH: Animals; Cytokines; Lipopolysaccharides; Lymphocytes; Mice; MicroRNAs; Porphyromonas gingivalis
From: West China Journal of Stomatology 2021;39(1):26-31
CountryChina
Language:English
Abstract: OBJECTIVES:This study aimed to investigate the effects of microRNA-146a (miR-146a) on the production of cytokines in lymphocytes stimulated by
METHODS:Lymphocytes were harvested from mouse spleen and cultured
RESULTS:Compared with non-LPS-stimulated group,
CONCLUSIONS:MiR-146a can provide a suitable microenvironment for bone formation by preventing the inflammatory effects of