- Author:
Qin HAO
1
;
Hui Xin LIU
2
;
Xue Xia HOU
1
;
Lin ZHANG
1
;
Xiao Na YANG
1
;
Kang Lin WAN
1
Author Information
- Publication Type:Journal Article
- Keywords: B-cell epitope; Borrelia burgdoferi; P66; Polymorphism
- MeSH: Bacterial Proteins/genetics*; Borrelia burgdorferi/genetics*; China; Cluster Analysis; Epitopes, B-Lymphocyte/genetics*; Genetic Markers; Genotype; Humans; Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Porins/genetics*
- From: Biomedical and Environmental Sciences 2021;34(5):364-371
- CountryChina
- Language:English
-
Abstract:
Objective:To study the polymorphism in P66 and its human B-cell epitopes of
Methods:Polymerase chain reaction (PCR) and sequencing were used to obtain the P66 sequences of 59 Chinese
Results:Results showed that genetic and amino acid diversity presented in the 66 kD protein of all 59 Chinese strains, especially in
Conclusion:In P66 of 59 Chinese strains, polymorphisms were widely distributed. More importantly, the P66 amino acid sequences of