Occupational Radiation Exposure and Changes in Thyroid Hormones in a Cohort of Chinese Medical Radiation Workers.

Qi Shan Guo; Ping Ruan; Wei Xu Huang; Dai Zheng Huang; Jia Chu Qiu

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Occupational Radiation Exposure and Changes in Thyroid Hormones in a Cohort of Chinese Medical Radiation Workers.

Author: Qi Shan GUO ^{1
,

2} ; Ping RUAN ^{2
,

3} ; Wei Xu HUANG ⁴ ; Dai Zheng HUANG ⁵ ; Jia Chu QIU ^{1
,

2}
Author Information

1. School of Public Health, Guangdong Pharmaceutical University, Guangzhou 510310, Guangdong, China
2. Guangdong Province Engineering & Technology Research Center for Medical 3D Printer and Personalized Medicine, Guangzhou 510006, Guangdong, China.
3. Department of Biomedical Engineering, Guangdong Pharmaceutical University, Guangzhou 510006, Guangdong, China
4. Guangdong Prevention and Treatment Center for Occupational Disease, Guangzhou 510300, Guangdong, China.
5. Department of Biomedical Engineering, Guangxi Medical University, Nanning 530021, Guangxi, China.
Publication Type:Journal Article
Keywords: Cohort; Occupational radiation; Thyroid function
MeSH: Adult; China; Cohort Studies; Female; Humans; Male; Middle Aged; Occupational Exposure/adverse effects*; Radiation Exposure/adverse effects*; Retrospective Studies; Thyroid Hormones/radiation effects*; Young Adult
From: Biomedical and Environmental Sciences 2021;34(4):282-289
CountryChina
Language:English
Abstract: Objective:This study aimed to evaluate the association between occupational radiation exposure and changes in thyroid hormone levels among medical radiation workers.
Methods:This retrospective cohort study included 2,946 radiation workers from 20 Guangzhou hospitals. Data on general characteristics, participant radiation dosimetry, and thyroid function test results [thyroid-stimulating hormone (TSH), triiodothyronine (T3), and thyroid hormone (T4)] were extracted from dosimetry and medical records. The generalized estimating equation was used to evaluate the trend of changes in thyroid hormone levels over time and was adjusted for age, gender, and occupation.
Results:The average annual effective dose was very low and showed a general downward trend. During the follow-up period, changes in T3 and T4 levels among radiation workers were -0.015 [95% confidence interval (
Conclusion:Thyroid hormone secretion might be affected even in low-dose radiation exposure environments.