Assessment of Retinal Ganglion Cell using Retinal Nerve Fiber Layer Photography in Age-related Macular Degeneration.
- Author:
Joo Youn OH
1
;
Tae Young CHUNG
;
Dong Myung KIM
;
Hyeong Gon YU
Author Information
1. Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. hgonyu@snu.ac.kr
- Publication Type:Original Article
- Keywords:
Age-related macular degeneration;
Age-related maculopathy;
Choroidal neovascularization;
Papillomacular bundle defect;
RNFL defect
- MeSH:
Choroidal Neovascularization;
Ganglion Cysts;
Humans;
Macular Degeneration*;
Nerve Fibers*;
Neurons;
Photography*;
Retinal Ganglion Cells*;
Retinaldehyde*
- From:Journal of the Korean Ophthalmological Society
2004;45(12):2036-2040
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To determine the loss of ganglion cell layer (GCL) neurons in patients with age-related macular degeneration (AMD) with choroidal neovascularization (CNV). METHODS: Retinal nerve fiber layer (RNFL) photography was taken in patients with AMD with CNV to assess the presence of RNFL defects in the papillomacular bundle area. Patients with other ocular disorders or a history of previous intraocular surgery or laser treatment were excluded from this study. RESULTS: Eighty-five eyes in 65 patients were included, of which only one (1.2%) showed papillomacular bundle defects in association with CNV. CONCLUSIONS: From this study, the majority of the patients with AMD with CNV had no papillomacular bundle defect, which demonstrates that considerable amount of GCL is maintained in AMD.
