Short-chain fatty acid butyrate acid attenuates atherosclerotic plaque formation in apolipoprotein E-knockout mice and the underlying mechanism.
- Author:
Hong-Bo BAI
1
;
Ping YANG
2
;
Han-Bin ZHANG
2
;
Yu-Lin LIU
2
;
Shu-Xiang FANG
2
;
Xiao-Yang XU
3
Author Information
1. Department of Physiology, School of Basic Medical Science, Guangzhou Medical University, Guangzhou 511436, China.
2. The Second Clinical School of Guangzhou Medical University, Guangzhou 510260, China.
3. The Second Clinical School of Guangzhou Medical University, Guangzhou 510260, China. xiaoyang-xu@gzhmu.edu.cn.
- Publication Type:Journal Article
- MeSH:
Animals;
Apolipoproteins E/genetics*;
Atherosclerosis/prevention & control*;
Butyrates/pharmacology*;
Caco-2 Cells;
Diet, High-Fat/adverse effects*;
Fatty Acids, Volatile;
Humans;
Mice;
Mice, Inbred C57BL;
Mice, Knockout;
Plaque, Atherosclerotic
- From:
Acta Physiologica Sinica
2021;73(1):42-50
- CountryChina
- Language:Chinese
-
Abstract:
This study was designed to evaluate the role of short-chain fatty acid butyrate acid on intestinal morphology and function, and atherosclerotic plaque formation in apolipoprotein E-knockout (ApoE
