Skin diseases in the Da Qing Diabetes Study: a cross-sectional study.
10.1097/CM9.0000000000001453
- Author:
Chang-Bing SHEN
1
;
Xin QIAN
2
;
Rui-Xing YU
3
;
Xue-Lei JI
4
;
Yin-Juan SHI
5
;
Jing GAO
6
;
Cheng-Xu LI
3
;
Ke-Ke LI
3
;
Wen-Min FEI
3
;
Xue SHEN
7
;
Zi-Yi WANG
3
;
Yang HAN
3
;
Xiao-Li NING
3
;
Randy KO
8
;
Yi-Hsiang HSU
9
;
Xian-Yong YIN
10
;
Guang-Wei LI
2
;
Yong CUI
3
Author Information
1. Department of Dermatology, Peking University Shenzhen Hospital, Shenzhen, Guangdong 518036, China.
2. Center of Endocrinology and Cardiology, Fu Wai Hospital, Chinese Academy of Medical Sciences, Beijing 100037, China.
3. Department of Dermatology, China-Japan Friendship Hospital, Beijing 100029, China.
4. Department of Endocrinology and Metabolism, Second People's Hospital of Wuhu, Wuhu, Anhui 241000, China.
5. Department of Dermatology, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, China.
6. Department of Dermatology, Second Affiliated Hospital, Anhui Medical University, Hefei, Anhui 230601, China.
7. Department of Dermatology, Chengdu Second People's Hospital, Chengdu, Sichuan 610017, China.
8. The University of New Mexico School of Medicine, Albuquerque, NM 87131, USA.
9. Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife and Harvard Medical School, Boston, MA 02131, USA.
10. Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA.
- Publication Type:Journal Article
- MeSH:
Aged;
Aged, 80 and over;
Blood Glucose;
Cross-Sectional Studies;
Diabetes Mellitus, Type 2/epidemiology*;
Female;
Glucose Intolerance/epidemiology*;
Glucose Tolerance Test;
Humans;
Male;
Middle Aged;
Skin Diseases/epidemiology*
- From:
Chinese Medical Journal
2021;134(10):1191-1198
- CountryChina
- Language:English
-
Abstract:
BACKGROUND:The prevalence of skin diseases and diabetes mellitus (DM) are prominent around the world. The current scope of knowledge regarding the prevalence of skin diseases and comorbidities with type 2 DM (T2DM) is limited, leading to limited recognition of the correlations between skin diseases and T2DM.
METHODS:We collected 383 subjects from the Da Qing Diabetes Study during the period from July 9th to September 1st, 2016. The subjects were categorized into three groups: Normal glucose tolerance (NGT), impaired glucose tolerance (IGT), and T2DM. The prevalence and clinical characteristics of skin diseases were recorded and investigated.
RESULTS:In this cross-sectional study, 383 individuals with ages ranging from 53 to 89-year-old were recruited. The overall prevalence of skin diseases was 93.5%, and 75.7% of individuals had two or more kinds of skin diseases. Additionally, there were 47 kinds of comorbid skin diseases in patients with T2DM, of which eight kinds of skin diseases had a prevalence >10%. The prevalence of skin diseases in NGT, IGT, and T2DM groups were 93.3%, 91.5%, and 96.6%, respectively; stratified analysis by categories showed a statistically significant difference in "disturbances of pigmentation" and "neurological and psychogenic dermatoses". The duration of T2DM also significantly associated with the prevalence of "disturbances of pigmentation" and "neurological and psychogenic dermatoses". Subsequently, the prevalence of "disturbances of pigmentation" was higher in males than females in NGT (P < 0.01) and T2DM (P < 0.01) groups. In addition, the difference in the prevalence of "disturbances of pigmentation" was also significant in NGT and T2DM groups (P < 0.01).
CONCLUSIONS:There was a high prevalence of skin diseases in the Da Qing Diabetes Study. To address the skin diseases in the Da Qing Diabetes Study, increased awareness and intervention measures should be implemented.
