Correlation between curative effect and 5-HTTLPR polymorphism in treatment of diarrhea-predominant irritable bowel syndrome with acupuncture for regulating
10.13703/j.0255-2930.20200313-k0002
- Author:
Jing GUO
1
;
Jian-Hua SUN
1
;
Lu CHEN
1
;
Hao GENG
1
;
Xiao-Liang WU
1
;
Ya-Fang SONG
1
;
Guo-Hui YANG
2
;
Rong-Rong SHEN
3
;
Min DING
4
;
Jin LU
5
;
Lian LIU
6
;
Xiang-Dong FANG
7
;
Li-Xia PEI
1
Author Information
1. Department of Acupuncture-Moxibustion and Rehabilitation, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province, China.
2. Department of Acupuncture-Moxibustion, Shuyang Hospital of TCM.
3. Department of Acupuncture-Moxibustion, Nantong Hospital of TCM.
4. Department of Acupuncture-Moxibustion, Wuxi Hospital of TCM.
5. Department of Acupuncture-Moxibustion, Nanjing Hospital of Chinese Medicine.
6. Department of Acupuncture-Moxibustion, Affiliated Hospital of Jiangsu University.
7. Department of Acupuncture-Moxibustion, Kunshan Hospital of TCM.
- Publication Type:Randomized Controlled Trial
- Keywords:
5-HT transporter gene-linked polymorphic region (5-HTTLPR);
acupuncture;
diarrhea-predominant irritable bowel syndrome (IBS-D);
gene polymorphism;
randomized controlled trial (RCT)
- MeSH:
Acupuncture Therapy;
Diarrhea/therapy*;
Humans;
Irritable Bowel Syndrome/therapy*;
Quality of Life;
Serotonin Plasma Membrane Transport Proteins/genetics*;
Spleen;
Treatment Outcome
- From:
Chinese Acupuncture & Moxibustion
2021;41(4):365-370
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To compare the curative effect on diarrhea-predominant irritable bowel syndrome (IBS-D) between acupuncture for regulating
METHODS:A total of 231 patients with IBS-D were randomized into an acupuncture group (154 cases) and a western medication group (77 cases) at the ratio of 2 to 1. In the acupuncture group, acupuncture was applied to acupoint regimen for regulating
RESULTS:After treatment and in follow-up, the total scores of IBS-SSS in the patients of the two groups were all reduced as compared with those before treatment (
CONCLUSION:Acupuncture for regulating
