Thunder-fire moxibustion combined with mifepristone for ovarian chocolate cyst dysmenorrhea with kidney deficiency and blood stasis: a randomized controlled trial.
10.13703/j.0255-2930.20191011-0002
- Author:
Ya-Bei CHEN
1
,
2
;
Jing LENG
3
;
Bo-Jie LIN
4
;
Ming-Hui XU
3
Author Information
1. College of Acupuncture-Moxibustion and Tuina, Guangxi University of CM, Nanning 530001, China
2. Nanning Huidong Outpatient Department, Nanning 530200, Guangxi Zhuang Autonomous Region.
3. College of Acupuncture-Moxibustion and Tuina, Guangxi University of CM, Nanning 530001, China.
4. Department of Plastic and Cosmetic Surgery, First Affiliated Hospital of Guangxi Medical University.
- Publication Type:Randomized Controlled Trial
- Keywords:
dysmenorrhea;
mifepristone;
ovarian chocolate cyst;
randomized controlled trial (RCT);
thunder-fire moxibustion
- MeSH:
Acupuncture Points;
Chocolate;
Cysts;
Dysmenorrhea/drug therapy*;
Female;
Humans;
Kidney;
Mifepristone;
Moxibustion
- From:
Chinese Acupuncture & Moxibustion
2021;41(2):161-164
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the clinical efficacy of thunder-fire moxibustion combined with mifepristone for ovarian chocolate cyst dysmenorrhea with kidney deficiency and blood stasis.
METHODS:Seventy patients were randomly divided into an observation group and a control group, 35 cases in each group. The patients in the the control group were treated with oral administration of mifepristone, 10 mg each time, once a day; based on the treatment of the control group, the patients in the observation group were treated with thunder-fire moxibustion at Guanyuan (CV 4), Zigong (EX-CA 1), Xuehai (SP 10), once every other day. Both the groups were treated for 3 months. The Cox menstrual symptom scale (CMSS) score, the maximum cross-sectional area of ectopic cyst, and the serum levels of transforming growth factor-β1 (TGF-β1) and interleukin-17 (IL-17) were observed before and after treatment in the two groups. The clinical efficacy was evaluated.
RESULTS:Compared before treatment, the severity scores and duration scores of CMSS as well as the serum levels of TGF-β1 were reduced after treatment in the two groups (
CONCLUSION:Thunder-fire moxibustion combined with mifepristone could significantly improve dysmenorrhea symptoms, shorten dysmenorrhea time and promote atrophy of ovarian heterotopic cyst in patients with ovarian chocolate cyst dysmenorrhea of kidney deficiency and blood stasis, and the mechanism may be related to the reduction of serum levels of TGF-β1 and IL-17.
