Effect of moxibustion on clinical symptoms, peripheral inflammatory indexes and T lymphocyte subsets in COVID-19 patients.
10.13703/j.0255-2930.20200507-k0003
- Author:
Lin LIU
1
;
Xiao-Yan XING
2
;
Dong-Chu HE
1
;
Wen-Chao YANG
1
;
Meng-Yun ZHANG
1
;
Wei WU
1
;
Xiao-Juan DING
1
;
Qiao YU
1
;
He-Song HUANG
1
;
Xiao-Bo SUN
2
;
Yong ZHANG
1
;
Jin-Sheng YANG
3
Author Information
1. Department of Integrative Traditional Chinese and Western Medicine, Central General Hospital of the Chinese PLA, Wuhan 430000, Hubei Province, China.
2. Institute of Medicinal Plant Development, China Academy of Medical Sciences and Peking Union Medical College.
3. Exchange and Cooperation Center of TCM Toward Taiwan, Hong Kong and Macao, State Administration of TCM, Beijing 100027.
- Publication Type:Randomized Controlled Trial
- Keywords:
T lymphocyte subsetsa;
asthmatic breathinga;
chest oppressiona;
coronavirus disease 2019 (COVID-19)a;
cougha;
inflammation indexes;
moxibustiona
- MeSH:
Acupuncture Points;
C-Reactive Protein/analysis*;
COVID-19/therapy*;
Humans;
Inflammation/therapy*;
Interleukin-6/blood*;
Leukocyte Count;
Moxibustion;
T-Lymphocyte Subsets/cytology*
- From:
Chinese Acupuncture & Moxibustion
2020;40(12):1271-1275
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To explore the therapeutic effect and the mechanism of the adjuvant treatment with moxibustion on coronavirus disease 2019 (COVID-19).
METHODS:A total of 95 patients with COVID-19 were randomly divided into a moxibustion group (45 cases) and a basic treatment group (50 cases). The routine treatment of western medicine was applied in the patients of both groups. In the moxibustion group, on the base of the treatment of western medicine, moxibustion was applied to Dazhui (GV 14), Feishu (BL 13), Qihai (CV 6) and Zusanli (ST 36), once daily and consecutively for 14 days. At the end of treatment courses, clinical symptom scores for cough, asthmatic breathing, chest oppression and short breath, as well as their remission rates were compared between the two groups before and after treatment. Before and after treatment, the white blood cell (WBC) count, the levels of c-reactive protein (CRP) and interleukin-6 (IL-6) and the absolute number of T lymphocyte subsets, i.e. , and of the peripheral blood were compared in the patients between the two groups. The principal component analysis was adopted to analyze the common data extracted from the above 10 clinical indexes variables and comprehensively evaluate the differences in the therapeutic effect of two regimens.
RESULTS:The clinical symptom scores were all decreased after treatment in both of the moxibustion group and the basic treatment group as compared with those before treatment (
CONCLUSION:On the base of the routine treatment with western medicine, moxibustion therapy supplemented relieves the clinical symptoms, reduces the levels of inflammatory indexes, i.e. IL-6 and CRP as well as improves the absolute number of peripheral T lymphocyte subsets. The clinical therapeutic effect of such regimen with moxibustion supplemented is significantly better than the simple routine treatment of western medicine.
