Polydocanol percutaneous sclerotherapy for the treatment of giant venular malformation of the lips and cheeks in adults
10.12016/j.issn.2096-1456.2021.09.006
- Author:
LI Fangfang
1
;
MENG Jian
1
;
ZHUANG Qianwei
2
Author Information
1. 1.School of Stomatology, Bengbu Medical University 2. Department of Stomatology, Central Hospital of Xuzhou City
2. Department of Stomatology, Central Hospital of Xuzhou City
- Publication Type:Journal Article
- Keywords:
vascular malformations;
venular malformation;
port wine stain;
sclerotherapy;
foam scleroagent;
polidocanol;
scleroagent
- From:
Journal of Prevention and Treatment for Stomatological Diseases
2021;29(9):611-616
- CountryChina
- Language:Chinese
-
Abstract:
Objective :To investigate the clinical effect of polidocanol sclerotherapy in the treatment of giant venular malformations of the lips and cheeks in adults.
Methods: From September 2019 to September 2020, 5 patients with huge venular malformations of the lips and cheeks (4 males, 1 female) admitted to Xuzhou Central Hospital were included in the study. All the patients were treated with local injection of polidocanol foam scleroagent, and all patients were followed up with a 3-week treatment course. If the clinical symptoms were not alleviated and the MRI examination showed that > 25% of the lesion remained, or it relapsed again after symptoms are stable, the patient needed to be treated again. The endpoints of treatment were: ①subsidence of clinical symptoms and MRI showing residual lesions < 25% in size; ②continuous treatment for 4 times without relief or aggravation of symptoms; ③a discontinuation of treatment.
Results:All 5 patients successfully completed the treatment and were injected 2 to 4 times during treatment. The curative effect was evaluated according to the Achauer standard, including grade Ⅰcurative effects in 1 patient, grade Ⅱ in 2 patients, grade Ⅲ in 2 patients. Among them, one patient suffered from erosion and bleeding in the lesion before the operation, and the symptoms were significantly improved postoperatively. No serious side effects were found except skin pigmentation in 1 case.
Conclusion:Local injection of polidocanol foam scleroagent is a safe and effective treatment method for adult giant venular malformations of the lips and cheeks, and it has a hemostatic effect on spontaneous bleeding invenular malformations.
- Full text:聚多卡醇经皮硬化治疗成人巨大唇颊部微静脉畸形.pdf