Research advances in clinical treatment of adult autoimmune hepatitis
10.3969/j.issn.1001-5256.2021.06.050
- VernacularTitle:成人自身免疫性肝炎临床治疗进展
- Author:
Mingyue ZHANG
1
;
Lin HAN
;
Ying SUN
;
Zhengsheng ZOU
Author Information
1. Graduate School, Medical School of Chinese PLA, Beijing 100039, China
- Publication Type:Research Article
- Keywords:
Hepatitis, Autoimmune;
Adult;
Therapeutics
- From:
Journal of Clinical Hepatology
2021;37(6):1459-1465
- CountryChina
- Language:Chinese
-
Abstract:
Autoimmune hepatitis (AIH) is an immune-mediated inflammatory injury of hepatocytes, which can develop into liver cirrhosis and end-stage liver disease. Timely immunosuppressive therapy can help patients achieve biochemical remission and even histological remission and thus improve prognosis. However, adverse drug reactions during treatment and recurrence after withdrawal are commonly seen, and therefore, standard therapy, dose reduction at the right time, and timely drug withdrawal are important for improving patients’ prognosis. This article summarizes the advances in guidelines for the diagnosis and treatment of AIH and related studies in China and globally, so as to provide a reference for clinicians in the treatment of AIH.
