Effect of salmeterol/fluticasone propionate combined with lip shrinkage respiration on the treatment of pneumoconiosis complicated COPD
10.11763/j.issn.2095-2619.2016.02.006
- Author:
Ying-Zi LIU
1
;
Feng-Ling WANG
;
Dong-Sheng WANG
1
;
Chun-Lan WANG
1
;
Guan-Ying YANG
1
;
Yong XU
1
Author Information
1. Daqing People's Hospital Daqing,Heilongjiang 163000,China
- Publication Type:Journal Article
- Keywords:
Pneumoconiosis;
Chronic obstructive pulmonary disease;
Salmeterol / fluticasone propionate;
Lip shrinkage respiration;
Small airway function;
Combined treatment
- From:
China Occupational Medicine
2016;43(02):148-151
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To observe the effects of combined treatment using salmeterol / fluticasone propionate and lip shrinkage respiration on the treatment of patients with pneumoconiosis complicated with chronic obstructive pulmonary disease( COPD). METHODS: By random number table method,98 patients with stable pneumoconiosis complicated with COPD were divided into 3 groups: drug treatment group( 33 cases) was treated only with inhalation of salmeterol /fluticasone propionate( 50 μg /500 μg),twice a day; lip shrinkage respiration group( 34 cases) was treated with abdominal breathing and lip shrinkage respiration training,three times daily for 15 min per session; combined treatment group( 31 cases) was treated with both the above treatments. Before and after 6 months of treatment,the lung function,the 6-minute walk distance and the oxygen saturation( Sa O2) were detected. The modified Medical Research Council( m MRC) Respiratory Questionnaire was used to evaluate the degree of dyspnea. RESULTS: After 6 months of treatment,the forced vital capacity percentage( FVC%),percentage of forced expiratory volume in one second( FEV1%),maximum ventilatory volume( MVV),6-minute walking distance,m MRC degree and the Sa O2 improved in the patients of these 3groups compared with those before treatment( P < 0. 05). Compared with the drug treatment group or lip shrinkage respiration group after treatment,the FVC%,FEV1%,MVV,6-minute walking distance and the Sa O2 in the combined treatment group were higher( P < 0. 05),and the m MRC degree was lower( P < 0. 05). CONCLUSION: Salmeterol /fluticasone propionate combined with lip shrinkage respiration treatment had better therapeutic effect than single treatment in treating patients with pneumoconiosis combined with COPD.