Progress in the construction of inner blood retinal barrier model in vitro
10.3980/j.issn.1672-5123.2021.6.10
- VernacularTitle:血-视网膜内屏障体外模型构建研究进展
- Author:
Chen Yuan
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Author Information
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5. Zhang Zhongjing College of Chinese Medicine, Nanyang Institute of Technology, Nanyang 473004, Henan Province, China
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8. College of Ophthalmology, Chengdu University of Traditional Chinese Medicine, Chengdu 610072, Sichuan Province, China
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10. College of Pharmacy, Chengdu University of Traditional Chinese Medince
11. Key Laboratory of Standardization of Chinese Herbal Medicines of Ministry of Education
12. State Key Laboratory Breeding Base of Systematic Research, Development and Utilization of Chinese Medicine Resources, Chengdu 610075, Sichuan Province, China
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14. Department of Ophthalmology, Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, Sichuan Province, China
- Publication Type:Journal Article
- Keywords:
inner blood-retinal barrier;
model in vitro;
research progress
- From:
International Eye Science
2021;21(6):991-995
- CountryChina
- Language:Chinese
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Abstract:
The blood-retinal barrier is an important structural basis for maintaining the homeostasis of the retinal environment, but there is still a lack of further research on its complete structure and function. The in vitro blood-retinal barrier model has the characteristics of controllable, efficient, fast and stable, and has become an effective tool to study the specific structure and function of the barrier. This paper mainly reviews the structure, function and in vitro model of blood-retinal barrier, which is helpful to promote the study of physiology, biochemistry, pathopharmacology and clinic of blood-retinal barrier. It also provides a common and key experimental basis for the study of fundus vascular diseases such as diabetic retinopathy.
- Full text:202106010.pdf