Research progress on risk factors of primary graft dysfunction after lung transplantation
10.3969/j.issn.1674-7445.2021.03.016
- VernacularTitle:肺移植术后原发性移植物功能障碍的危险因素研究进展
- Author:
Chunlan HU
1
;
Huizhi YU
;
Jing WANG
;
Xiaoshan LI
;
Chunxiao HU
Author Information
1. Department of Anesthesiology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi 214023, China
- Publication Type:Research Article
- Keywords:
Lung transplantation;
Primary graft dysfunction;
Expanded criteria donor;
Reactive oxygen species;
Extracorporeal membrane oxygenation;
Ex vivo lung perfusion;
Cardiopulmonary bypass;
Transfusion-related lung injury
- From:
Organ Transplantation
2021;12(3):357-
- CountryChina
- Language:Chinese
-
Abstract:
Lung transplantation is the only effective approach to treat end-stage lung diseases. Nevertheless, early prognosis of lung transplant recipients is significantly worse than that of other solid organ transplant recipients. Primary graft dysfunction (PGD) is one of the main causes affecting clinical prognosis of the recipients. PGD is an early acute lung injury after lung transplantation, which is the main cause of early death of lung transplant recipients. Risk factors of PGD after lung transplantation consist of donor, recipient and operation, etc. In this article, the risk factors of PGD after lung transplantation were reviewed, aiming to provide reference for clinical practice.
