Awareness rate of adverse events following immunization among Chinese parents: a meta-analysis
10.19485/j.cnki.issn2096-5087.2021.03.008
- Author:
YAN Bo
;
ZHOU Qian Yi
;
ZHENG Xiao Hui
;
YU Zhao Feng
;
LU Ying
;
LIU Zi Yu
;
CHEN Wei Qing
- Publication Type:Journal Article
- Keywords:
adverse events following immunization awareness rate parents meta-analysis
- From:
Journal of Preventive Medicine
2021;33(3):250-254
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To learn the awareness rate of adverse events following immunization ( AEFI ) among Chinese parents, so as to provide suggestions for promoting vaccination.
Methods:We searched relevant articles published before 24th June, 2020 from CNKI, Wanfang, VIP, CBM, PubMed and Web of Science, calculated the pooled awareness rate and 95% confidence interval ( CI ) , conducted Egger＇s test for publication bias and sensitivity analysis for stability of results.
Results:Eight articles using cross-sectional design were included after screening from 235 initial records. Among 5 433 subjects, the pooled awareness rate of AEFI was 66.76% ( 95%CI: 52.75%-78.33% ) . Non-immigrant population possessed a higher awareness rate ( 67.32% ) compared with the immigrant population ( 56.54% ) . The parents with different levels of education showed various awareness rate of AEFI ( P<0.05 ) . The awareness rates of "children should be observed for at least 30 minutes after vaccination","slight adverse effects were commonly seen after vaccination","local redness and induration might occur after diphtheria-tetanus-pertussis ( DTP ) immunization","polio vaccine might bring mild diarrhea" were 86.18%, 66.76%, 41.89% and 30.22%, respectively. Egger＇s test showed that there was no publication bias. Sensitivity analysis indicated that the results were robust.
Conclusion:The pooled awareness rate of AEFI among Chinese parents is 66.76%, with lower rates found in the parents who are immigrants and have lower level of education.
- Full text:中国儿童家长疑似预防接种异常反应知晓率的Meta分析.pdf
