Investigation on iodine nutritional status and thyroid function of women in early pregnancy after the implementation of a new standard of iodized salt in Chengde
10.3969/j.issn.1006-2483.2021.02.035
- VernacularTitle:承德地区盐碘新标准实施后孕早期妇女碘营养状况及甲状腺功能调查
- Author:
Dan LIU
1
;
Dongmei WANG
1
;
Fengjie HAO
1
;
Lidong WANG
1
Author Information
1. Department of Endocrinology, Chengde Central Hospital, Chengde, Hebei 067000, China
- Publication Type:Journal Article
- Keywords:
Early pregnancy women;
Iodine nutritional status;
Thyroid function
- From:
Journal of Public Health and Preventive Medicine
2021;32(2):144-146
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the iodine nutritional status and thyroid function of women in early pregnancy after the implementation of a new standard of iodized salt in Chengde. Methods A total of 136 early pregnancy women who had lived in Chengde were randomly selected in this study from January 2018 to March 2020. A questionnaire survey was conducted. The iodized salt, urine and blood samples of the pregnant women were collected to analyze the salt iodine concentration, serum iodine, urinary iodine, serum thyroid stimulating hormone (TSH), free triiodothyronine (FT3), and free thyroxine (FT4). Results In 2018 and 2019, the iodized salt coverage rates were 96.97% and 98.57%, the non-iodized salt rates were 3.03% and 1.43%, the iodized salt qualification rates were 95.45% and 97.14%, and the qualified iodized salt consumption rates were 93.94% and 92.86%, respectively. In addition, the median of iodized salt consumption was 22.20 mg/kg and 25.51 mg/kg, in 2018 and 2019, respectively. There was a statistically significant difference in the median urine iodine from 2018 to 2019 among women in early pregnancy (P<0.05). The urinary iodine frequency distribution and detection rate of thyroid diseases of women in early pregnancy had no significant difference in 2018 and 2019, and no significant difference was found in the detection rate of thyroid diseases of women in low-iodine group, appropriate iodine group and high-iodine group (P>0.05). Conclusion After the implementation of a new standard of iodized salt in Chengde, the iodine nutritional status of early pregnant women in 2019 was significantly improved, but there was still a small amount of insufficient iodine intake. The incidence of thyroid diseases in early pregnant women with abnormal iodine intake was higher than that in early pregnant women with appropriate iodine intake.