A Case of Dariers Disease Treated with Adapalene.
- Author:
Eul Sang HWANG
1
;
Yong Ju KIM
;
Dong Soo YU
;
Hae Jun SONG
;
Chil Hwan OH
Author Information
1. Department of Dermatology, College of Medicine, Korea University, Seoul, Korea. choh@korea.ac.kr
- Publication Type:Case Report
- Keywords:
Dariers disease;
Adapalene
- MeSH:
Anti-Inflammatory Agents;
Darier Disease*;
Adapalene
- From:Korean Journal of Dermatology
2005;43(3):425-427
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Dariers disease is inherited as an autosomal dominant trait and characterized by follicular pruritic hyperkeratotic papules. The onset is usually in late childhood and the course of the disease is chronic and slowly progressive in most cases. Dariers disease is refractory to treatment with most conventional keratolytics and anti-inflammatory agents. To date, oral and topical retinoid products have been the mainstay therapy for this population, but local as well as systemic side effects often limit their effectiveness. We present a case of localized Dariers disease which responded promptly to the topical application of adapalene 0.1% gel without side effects. A review of treatment for Dariers disease also is presented.
