Polio antibody levels in infants during 2015-2016 in Shanghai before and after polio vaccination strategy adjustment

VernacularTitle:2015-2016年上海市脊髓灰质炎疫苗免疫策略调整前后婴儿抗体水平变化
Author: Min-yong LIU ¹ ; Zhuo-ying HUANG ; Jing LU ; Jian-ping YANG ; Yu-ying YANG
Author Information

1. Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China
Publication Type:Research Article
Keywords: poliomyelitis; immunization; vaccine; antibody
From: Shanghai Journal of Preventive Medicine 2020;32(8):627-
CountryChina
Language:Chinese
Abstract: Objective To investigate the neutralized antibody level of poliomyelitis among healthy children before and after implementation of the new immunization strategy in Shanghai. Methods The poliomyelitis levels of healthy children were detected by neutralization test of the micro cells. Results The neutralizing antibody positive rates were 100% for polioⅠand polioⅢ before and after implementation of the new immunization strategy.GMTs (geometric mean titers) for polioⅠwere 1:1 047.46 before it, and 1:254.70 after it; those for polio Ⅲ were 1:513.52 before it and 1:185.49 after it. Conclusion The neutralized antibody levels of the poliomyelitis among healthy infants maintain a high level before and after implementing the new immunization strategy in Shanghai.