Key issues on the evolution, related epidemiological features, and specific prophylaxis of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2)
10.19428/j.cnki.sjpm.2020.20587
- VernacularTitle:新型冠状病毒进化、相关流行特征和特异性防控中的关键问题
- Author:
Guang-wen CAO
1
Author Information
1. Department of Epidemiology, The Second Military Medical University, Shanghai 200433, China
- Publication Type:Research Article
- Keywords:
SARS-CoV-2;
COVID-19;
viral evolution;
prophylaxis
- From:
Shanghai Journal of Preventive Medicine
2020;32(9):697-
- CountryChina
- Language:Chinese
-
Abstract:
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) is in the pandemic.SARS-CoV-2 is believed to originate from natural evolution.This RNA virus keeps evolving, even during spillover into humans via intermediate hosts.The evolutionary trend of SARS-CoV-2 in humans is characterized as an increased human-to-human transmission.The current major countermeasures against COVID-19 pandemic remain to be public health interventions, specifically targeting to the transmission pathway.In addition, the key point for the prophylaxis is to screen and isolate asymptomatic SARS-CoV-2 carriers, which may be a crucial source of infection.The efficiency of active immunization using vaccine to protect susceptible population needs to be extensively evaluated in population of large scale.
