Outcomes of surgical treatment of 29 patients with stages Ⅱ-Ⅲ bisphosphonate-related osteonecrosis of the jaw
10.12016/j.issn.2096-1456.2021.06.006
- Author:
YAN Xingquan
1
;
NAN Xinrong
1
;
ZHANG Zejun
2
;
ZHANG Qi
2
Author Information
1. Department of Stomatology, The First Hospital, Shanxi Medical University
2. School of Stomatology, Shanxi Medical University
- Publication Type:Journal Article
- Keywords:
bisphosphonates;
osteonecrosis of the jaw;
surgical treatment;
curettage of local lesions;
subtotal resection of maxilla;
partial resection of mandible
- From:
Journal of Prevention and Treatment for Stomatological Diseases
2021;29(6):395-399
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To examine the outcome of surgical treatment in patients with stages Ⅱ-Ⅲ bisphosphonate-related osteonecrosis of the jaw.
Methods:Twenty-nine patients with bisphosphonate-related osteonecrosis of the jaw were examined. The patients were followed up for more than 6 months, and the treatment outcome was reviewed.
Results: After curettage of local lesions, 19 out of the 21 patients were cured, and 2 were relieved of symptoms. Six patients underwent subtotal resection of the maxilla, and the symptoms disappeared completely after the surgery. Two patients underwent partial resection of the mandible and recovered.
Conclusion:Surgical debridement is an effective measure for the treatment of patients with bisphosphonate-related osteonecrosis of the jaw in stages Ⅱ-Ⅲ. In most cases, curettage of local lesions via the intraoral approach can completely remove sequestrum and inflammatory granulomatous tissue. Subtotal maxillary resection or partial mandible resection is performed when the bone death reaches the level of the maxillary sinus floor or continues to the mandible. By timely surgical intervention, the bone lesion is removed to maintain the sterile, active bone microenvironment locally.
- Full text:29例Ⅱ期和Ⅲ期双膦酸盐相关颌骨坏死的手术疗效.pdf
