Application of the calculated electrophysiological parameters in early diagnosis of carpal tunnel syndrome
- Author:
Jin-Hua Zhang
;
Baoyu Yuan
;
Fu-Ling Yan
- Publication Type:Journal Article
- Keywords:
: Carpal tunnel syndrome (CTS);
calculated electrophysiological parameters;
early diagnosis
- From:Neurology Asia
2020;25(2):139-143
- CountryMalaysia
- Language:English
-
Abstract:
Objective: To investigate the application of the calculated electrophysiological parameters in early
diagnosis of carpal tunnel syndrome (CTS). Methods: 44 patients (60 hands) with a diagnosis of
CTS and 31 healthy volunteers (44 hands) were enrolled. Acquired indicators include median nerve
distal motor latency (DML), complex muscle action potential (CMAP) amplitude, conduction velocity
(MCV), median nerve sensory nerve action potential (SNAP) amplitude, and conduction velocity
(SCV). Then the terminal latency index (TLI), the residual latency (RL), and the difference in peak
sensory latencies between the median and ulnar nerves (ΔPSL) were calculated. Results: The two
groups were matched in age and gender distribution. The CTS group showed significant difference
in SCV, DML, SNAP, and CMAP compared with the control group. The sensitivity, specificity, cutoff value, Youden index, and area under the curve of each indicator are respectively as follows: TLI
(0.733, 0.932, 0.622, 0.629, and 0.877), RL (0.750, 0.977, 1.334, 0.727, and 0.907), ΔPSL (0.950,
0.841, 0.150, 0.791, and 0.942), SCV (0.950, 0.796, 56.5, 0.746, and 0.946), DML (0.867, 0.932,
3.55, 0.799, and 0.930), SNAP (0.683, 0.932, 21.68, 0.615, and 0.844), and CMAP (0.683, 0.773,
8.76, 0.456, and 0.758).
Conclusion: The calculated electrophysiological parameters have higher sensitivities and specificities
relative to a single electrophysiological parameter, which could greatly improve the accuracy of early
diagnosis of CTS.
- Full text:7.2020my0023.pdf
