Medication evaluation and adverse reaction monitoring in patient on peritoneal dialysis with pancytopenia induced by vancomycin
10.3969/j.issn.1006-0111.202008042
- VernacularTitle:万古霉素致腹膜透析患者全血细胞减少的用药分析与不良反应监护
- Author:
Bin ZHANG
1
;
Yunling DONG
2
;
Yingxin XIE
1
;
Yueyue LI
1
;
Xiuxiu JIAO
1
;
Yongfang YUAN
1
Author Information
1. .
2. Department of Pharmacy, People’s Hospital of Puyang, Puyang 457000, China.
- Keywords:
vancomycin;
peritoneal dialysis;
pancytopenia;
individualized treatment;
adverse drug reaction reporting system
- From:
Journal of Pharmaceutical Practice
2021;39(2):169-173
- CountryChina
- Language:Chinese
-
Abstract:
Objective To provide reference for anti-infection treatment and individual pharmaceutical care in patient on peritoneal dialysis. Methods The plasma concentration of vancomycin in patient on peritoneal dialysis was monitored by clinical pharmacists. The anti-infection treatment plan was evaluated and adjusted according to the bacterial culture and drug sensitivity results of the abdominal dialysis fluid. The adverse reactions of pancytopenia induced by vancomycin were documented. Results Infection in the patient on peritoneal dialysis was effectively controlled. The related indicators of pancytopenia were improved. Conclusion A case of pancytopenia induced by vancomycin in the patient on peritoneal dialysis was analyzed to get clinical staff's attention to this adverse reaction and improve the safety of vancomycin administration.